4365-0047 Screening compound: 3-amino-N-(5-phenyl-1,3,4-thiadiazol-2-yl)-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide

4365-0047 Screening compound: 3-amino-N-(5-phenyl-1,3,4-thiadiazol-2-yl)-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide
4365-0047 Screening compound: 3-amino-N-(5-phenyl-1,3,4-thiadiazol-2-yl)-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 4365-0047
3-amino-N-(5-phenyl-1,3,4-thiadiazol-2-yl)-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4365-0047

Molecular Formula

C20H17N5OS2 (C20 H17 N5 OS2)

Compound Name

3-amino-N-(5-phenyl-1,3,4-thiadiazol-2-yl)-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide

IUPAC name

3-amino-N-(5-phenyl-134-thiadiazol-2-yl)-5H6H7H8H-thieno[23-b]quinoline-2-carboxamide

SMILES

Nc1c(C(Nc2nnc(-c3ccccc3)s2)=O)sc2c1cc(CCCC1)c1n2

InChI

InChI=1S/C20H17N5OS2/c21-15-13-10-12-8-4-5-9-14(12)22-19(13)27-16(15)17(26)23-20-25-24-18(28-20)11-6-2-1-3-7-11/h1-3,6-7,10H,4-5,8-9,21H2,(H,23,25,26)

InChI Key

PBNPLYUJGISUIK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01962614

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.765

Distribution Coefficient, logD

4.751

Water Solubility, LogSw

-4.92

Polar Surface Area

77.131

Acid Dissociation Constant (pKa)

10.43

Base Dissociation Constant (pKb)

5.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

4365-0047 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

CORONAVIRUS Library (20774 compounds)

Nucleic Acid Ligands (8311 compounds)

PLpro Library (6343 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with 4365-0047 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4365-0047?
Check Price and Availability of 4365-0047, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4365-0047 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4365-0047
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4365-0047
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4365-0047 available by request