4369-0011 Screening compound: 2-(4-methylphenyl)-2-oxoethyl 2-[(4-chlorophenyl)formamido]-3-(1H-indol-3-yl)propanoate

4369-0011 Screening compound: 2-(4-methylphenyl)-2-oxoethyl 2-[(4-chlorophenyl)formamido]-3-(1H-indol-3-yl)propanoate
4369-0011 Screening compound: 2-(4-methylphenyl)-2-oxoethyl 2-[(4-chlorophenyl)formamido]-3-(1H-indol-3-yl)propanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound 4369-0011
2-(4-methylphenyl)-2-oxoethyl 2-[(4-chlorophenyl)formamido]-3-(1H-indol-3-yl)propanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4369-0011

Molecular Formula

C27H23ClN2O4 (C27 H23 ClN2 O4)

Compound Name

2-(4-methylphenyl)-2-oxoethyl 2-[(4-chlorophenyl)formamido]-3-(1H-indol-3-yl)propanoate

IUPAC name

2-(4-methylphenyl)-2-oxoethyl 2-[(4-chlorophenyl)formamido]-3-(1H-indol-3-yl)propanoate

SMILES

Cc(cc1)ccc1C(COC(C(Cc1c[nH]c2c1cccc2)NC(c(cc1)ccc1Cl)=O)=O)=O

InChI

InChI=1S/C27H23ClN2O4/c1-17-6-8-18(9-7-17)25(31)16-34-27(33)24(30-26(32)19-10-12-21(28)13-11-19)14-20-15-29-23-5-3-2-4-22(20)23/h2-13,15,24,29H,14,16H2,1H3,(H,30,32)/t24-/m0/s1

InChI Key

PGVOYNFTWCRULC-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD06349531

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.94

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.931

Distribution Coefficient, logD

4.931

Water Solubility, LogSw

-5.06

Polar Surface Area

68.258

Acid Dissociation Constant (pKa)

10.72

Base Dissociation Constant (pKb)

-3.35

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

14.80

4369-0011 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 4369-0011 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4369-0011?
Check Price and Availability of 4369-0011, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4369-0011 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4369-0011
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4369-0011
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4369-0011 available by request