4383-0003 Screening compound: 4-(3-chlorophenyl)-N-(3,4-difluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

4383-0003 Screening compound: 4-(3-chlorophenyl)-N-(3,4-difluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
4383-0003 Screening compound: 4-(3-chlorophenyl)-N-(3,4-difluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 4383-0003
4-(3-chlorophenyl)-N-(3,4-difluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4383-0003

Molecular Formula

C18H14ClF2N3O2 (C18 H14 ClF2 N3 O2)

Compound Name

4-(3-chlorophenyl)-N-(3,4-difluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

IUPAC name

4-(3-chlorophenyl)-N-(34-difluorophenyl)-6-methyl-2-oxo-1234-tetrahydropyrimidine-5-carboxamide

SMILES

CC(NC(NC1c2cccc(Cl)c2)=O)=C1C(Nc(cc1)cc(F)c1F)=O

InChI

InChI=1S/C18H14ClF2N3O2/c1-9-15(17(25)23-12-5-6-13(20)14(21)8-12)16(24-18(26)22-9)10-3-2-4-11(19)7-10/h2-8,16H,1H3,(H,23,25)(H2,22,24,26)/t16-/m0/s1

InChI Key

BQZWQRMNRCCTPM-INIZCTEOSA-N

MDL Number (MFCD)

MFCD02844676

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.78

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.274

Distribution Coefficient, logD

3.089

Water Solubility, LogSw

-3.67

Polar Surface Area

58.783

Acid Dissociation Constant (pKa)

7.68

Base Dissociation Constant (pKb)

-3.32

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

11.10

4383-0003 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Nervous system

References: we are preparing a list of scientific research reports with 4383-0003 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4383-0003?
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What is the minimum amount of 4383-0003 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4383-0003
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4383-0003
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4383-0003 available by request