4463-0192 Screening compound: (3Z)-5-bromo-3-[2-(quinolin-2-yl)hydrazin-1-ylidene]-2,3-dihydro-1H-indol-2-one

4463-0192 Screening compound: (3Z)-5-bromo-3-[2-(quinolin-2-yl)hydrazin-1-ylidene]-2,3-dihydro-1H-indol-2-one
4463-0192 Screening compound: (3Z)-5-bromo-3-[2-(quinolin-2-yl)hydrazin-1-ylidene]-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 4463-0192
(3Z)-5-bromo-3-[2-(quinolin-2-yl)hydrazin-1-ylidene]-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4463-0192

Molecular Formula

C17H11BrN4O (C17 H11 BrN4 O)

Compound Name

(3Z)-5-bromo-3-[2-(quinolin-2-yl)hydrazin-1-ylidene]-2,3-dihydro-1H-indol-2-one

IUPAC name

(3Z)-5-bromo-3-[2-(quinolin-2-yl)hydrazin-1-ylidene]-23-dihydro-1H-indol-2-one

SMILES

O=C1Nc(ccc(Br)c2)c2/C1=N/Nc1nc2ccccc2cc1

InChI

InChI=1S/C17H11BrN4O/c18-11-6-7-14-12(9-11)16(17(23)20-14)22-21-15-8-5-10-3-1-2-4-13(10)19-15/h1-9H,(H,19,21)(H,20,22,23)

InChI Key

IBDGKFKZLHZGIH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01653898

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.2

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.715

Distribution Coefficient, logD

4.715

Water Solubility, LogSw

-5.29

Polar Surface Area

54.083

Acid Dissociation Constant (pKa)

12.37

Base Dissociation Constant (pKb)

3.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

4463-0192 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with 4463-0192 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4463-0192?
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What is the minimum amount of 4463-0192 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4463-0192
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4463-0192
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4463-0192 available by request