4477-1841 Screening compound: 2-(2-ethylphenyl)-4,4,8-trimethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

4477-1841 Screening compound: 2-(2-ethylphenyl)-4,4,8-trimethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione
4477-1841 Screening compound: 2-(2-ethylphenyl)-4,4,8-trimethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione alternative view

Chemical Structure Depiction of ChemDiv screening compound 4477-1841
2-(2-ethylphenyl)-4,4,8-trimethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4477-1841

Molecular Formula

C21H22N2S2 (C21 H22 N2 S2)

Compound Name

2-(2-ethylphenyl)-4,4,8-trimethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

IUPAC name

2-(2-ethylphenyl)-448-trimethyl-1H2H4H5H-[12]thiazolo[54-c]quinoline-1-thione

SMILES

CCc(cccc1)c1N(C1=S)SC2=C1c(cc(C)cc1)c1NC2(C)C

InChI

InChI=1S/C21H22N2S2/c1-5-14-8-6-7-9-17(14)23-20(24)18-15-12-13(2)10-11-16(15)22-21(3,4)19(18)25-23/h6-12,22H,5H2,1-4H3

InChI Key

XYXPNIKZQPLRER-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01975592

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.55

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

6.165

Distribution Coefficient, logD

5.226

Water Solubility, LogSw

-5.85

Polar Surface Area

14.405

Acid Dissociation Constant (pKa)

17.92

Base Dissociation Constant (pKb)

8.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

4477-1841 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 4477-1841 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4477-1841?
Check Price and Availability of 4477-1841, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4477-1841 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4477-1841
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4477-1841
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4477-1841 available by request