4527-0028 Screening compound: 5-(4-methoxyphenyl)-2-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

4527-0028 Screening compound: 5-(4-methoxyphenyl)-2-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
4527-0028 Screening compound: 5-(4-methoxyphenyl)-2-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound 4527-0028
5-(4-methoxyphenyl)-2-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4527-0028

Molecular Formula

C21H16F3N3O (C21 H16 F3 N3 O)

Compound Name

5-(4-methoxyphenyl)-2-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

IUPAC name

5-(4-methoxyphenyl)-2-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine

SMILES

Cc(cc1)ccc1-c1nn2c(C(F)(F)F)cc(-c(cc3)ccc3OC)nc2c1

InChI

InChI=1S/C21H16F3N3O/c1-13-3-5-15(6-4-13)18-12-20-25-17(14-7-9-16(28-2)10-8-14)11-19(21(22,23)24)27(20)26-18/h3-12H,1-2H3

InChI Key

FMQKXUOUVRFXQD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01764005

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.37

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.160

Distribution Coefficient, logD

6.160

Water Solubility, LogSw

-5.66

Polar Surface Area

25.670

Acid Dissociation Constant (pKa)

28.37

Base Dissociation Constant (pKb)

3.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

4527-0028 in Drug Discovery

Included in Screening Libraries

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels
  • Ion Channels

References: we are preparing a list of scientific research reports with 4527-0028 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4527-0028?
Check Price and Availability of 4527-0028, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4527-0028 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4527-0028
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4527-0028
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4527-0028 available by request