4606-0673 Screening compound: 2,4,6-trimethyl-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}benzene-1-sulfonamide

4606-0673 Screening compound: 2,4,6-trimethyl-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}benzene-1-sulfonamide
4606-0673 Screening compound: 2,4,6-trimethyl-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 4606-0673
2,4,6-trimethyl-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4606-0673

Molecular Formula

C19H20N4O4S2 (C19 H20 N4 O4 S2)

Compound Name

2,4,6-trimethyl-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}benzene-1-sulfonamide

IUPAC name

246-trimethyl-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}benzene-1-sulfonamide

SMILES

Cc(cc1C)cc(C)c1S(Nc(cc1)ccc1S(Nc1ncccn1)(=O)=O)(=O)=O

InChI

InChI=1S/C19H20N4O4S2/c1-13-11-14(2)18(15(3)12-13)29(26,27)22-16-5-7-17(8-6-16)28(24,25)23-19-20-9-4-10-21-19/h4-12,22H,1-3H3,(H,20,21,23)

InChI Key

DRHOZAFCAWVXSR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02315798

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.52

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.103

Distribution Coefficient, logD

1.116

Water Solubility, LogSw

-3.30

Polar Surface Area

102.107

Acid Dissociation Constant (pKa)

5.42

Base Dissociation Constant (pKb)

-2.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

4606-0673 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Glucocorticoid receptors Library (4806 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Nuclear receptors
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 4606-0673 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4606-0673?
Check Price and Availability of 4606-0673, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4606-0673 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4606-0673
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4606-0673
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4606-0673 available by request