4770-1368 Screening compound: N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2,2-bis(trifluoromethyl)butanamide

4770-1368 Screening compound: N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2,2-bis(trifluoromethyl)butanamide
4770-1368 Screening compound: N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2,2-bis(trifluoromethyl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 4770-1368
N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2,2-bis(trifluoromethyl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4770-1368

Molecular Formula

C18H18F6N4O3S (C18 H18 F6 N4 O3 S)

Compound Name

N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2,2-bis(trifluoromethyl)butanamide

IUPAC name

N-{4-[(46-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-22-bis(trifluoromethyl)butanamide

SMILES

CCC(C(F)(F)F)(C(F)(F)F)C(Nc(cc1)ccc1S(Nc1nc(C)cc(C)n1)(=O)=O)=O

InChI

InChI=1S/C18H18F6N4O3S/c1-4-16(17(19,20)21,18(22,23)24)14(29)27-12-5-7-13(8-6-12)32(30,31)28-15-25-10(2)9-11(3)26-15/h5-9H,4H2,1-3H3,(H,27,29)(H,25,26,28)

InChI Key

UUTGZCQGQPRQAR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00755742

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.42

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.724

Distribution Coefficient, logD

3.242

Water Solubility, LogSw

-3.97

Polar Surface Area

83.569

Acid Dissociation Constant (pKa)

7.09

Base Dissociation Constant (pKb)

-0.34

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

4770-1368 in Drug Discovery

Included in Screening Libraries

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 4770-1368 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4770-1368?
Check Price and Availability of 4770-1368, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4770-1368 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4770-1368
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4770-1368
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4770-1368 available by request