4908-0007 Screening compound: N-[(2,4-dichlorophenyl)(8-hydroxyquinolin-7-yl)methyl]-2-methylpropanamide

4908-0007 Screening compound: N-[(2,4-dichlorophenyl)(8-hydroxyquinolin-7-yl)methyl]-2-methylpropanamide
4908-0007 Screening compound: N-[(2,4-dichlorophenyl)(8-hydroxyquinolin-7-yl)methyl]-2-methylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 4908-0007
N-[(2,4-dichlorophenyl)(8-hydroxyquinolin-7-yl)methyl]-2-methylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4908-0007

Molecular Formula

C20H18Cl2N2O2 (C20 H18 Cl2 N2 O2)

Compound Name

N-[(2,4-dichlorophenyl)(8-hydroxyquinolin-7-yl)methyl]-2-methylpropanamide

IUPAC name

N-[(24-dichlorophenyl)(8-hydroxyquinolin-7-yl)methyl]-2-methylpropanamide

SMILES

CC(C)C(NC(c(ccc(Cl)c1)c1Cl)c(ccc1cccnc11)c1O)=O

InChI

InChI=1S/C20H18Cl2N2O2/c1-11(2)20(26)24-18(14-8-6-13(21)10-16(14)22)15-7-5-12-4-3-9-23-17(12)19(15)25/h3-11,18,25H,1-2H3,(H,24,26)/t18-/m0/s1

InChI Key

GUGJXJDURCSDQV-SFHVURJKSA-N

MDL Number (MFCD)

MFCD02732268

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.28

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.261

Distribution Coefficient, logD

5.259

Water Solubility, LogSw

-5.46

Polar Surface Area

49.016

Acid Dissociation Constant (pKa)

9.84

Base Dissociation Constant (pKb)

4.21

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

4908-0007 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS targets activity set (6557 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

DGK Inhibitors Library (10558 compounds)

Human GPCR Annotated Library (5539 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with 4908-0007 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4908-0007?
Check Price and Availability of 4908-0007, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4908-0007 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4908-0007
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4908-0007
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4908-0007 available by request