5186-0143 Screening compound: 4-({4-[4-(propan-2-yl)phenyl]-1,3-thiazol-2-yl}amino)benzene-1-sulfonamide

5186-0143 Screening compound: 4-({4-[4-(propan-2-yl)phenyl]-1,3-thiazol-2-yl}amino)benzene-1-sulfonamide
5186-0143 Screening compound: 4-({4-[4-(propan-2-yl)phenyl]-1,3-thiazol-2-yl}amino)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 5186-0143
4-({4-[4-(propan-2-yl)phenyl]-1,3-thiazol-2-yl}amino)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5186-0143

Molecular Formula

C18H19N3O2S2 (C18 H19 N3 O2 S2)

Compound Name

4-({4-[4-(propan-2-yl)phenyl]-1,3-thiazol-2-yl}amino)benzene-1-sulfonamide

IUPAC name

4-({4-[4-(propan-2-yl)phenyl]-13-thiazol-2-yl}amino)benzene-1-sulfonamide

SMILES

CC(C)c(cc1)ccc1-c1csc(Nc(cc2)ccc2S(N)(=O)=O)n1

InChI

InChI=1S/C18H19N3O2S2/c1-12(2)13-3-5-14(6-4-13)17-11-24-18(21-17)20-15-7-9-16(10-8-15)25(19,22)23/h3-12H,1-2H3,(H,20,21)(H2,19,22,23)

InChI Key

NSGWMTUAYFJGFA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03542404

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.985

Distribution Coefficient, logD

4.984

Water Solubility, LogSw

-4.71

Polar Surface Area

69.529

Acid Dissociation Constant (pKa)

10.01

Base Dissociation Constant (pKb)

3.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

5186-0143 in Drug Discovery

Included in Screening Libraries

Proline Kinase Library (2105 compounds)

SmartTM Library (51161 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Epigenetics Focused Set (26518 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 5186-0143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5186-0143?
Check Price and Availability of 5186-0143, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5186-0143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5186-0143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5186-0143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5186-0143 available by request