5186-0144 Screening compound: N-(4,6-dimethylpyrimidin-2-yl)-4-({4-[4-(propan-2-yl)phenyl]-1,3-thiazol-2-yl}amino)benzene-1-sulfonamide

5186-0144 Screening compound: N-(4,6-dimethylpyrimidin-2-yl)-4-({4-[4-(propan-2-yl)phenyl]-1,3-thiazol-2-yl}amino)benzene-1-sulfonamide
5186-0144 Screening compound: N-(4,6-dimethylpyrimidin-2-yl)-4-({4-[4-(propan-2-yl)phenyl]-1,3-thiazol-2-yl}amino)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 5186-0144
N-(4,6-dimethylpyrimidin-2-yl)-4-({4-[4-(propan-2-yl)phenyl]-1,3-thiazol-2-yl}amino)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5186-0144

Molecular Formula

C24H25N5O2S2 (C24 H25 N5 O2 S2)

Compound Name

N-(4,6-dimethylpyrimidin-2-yl)-4-({4-[4-(propan-2-yl)phenyl]-1,3-thiazol-2-yl}amino)benzene-1-sulfonamide

IUPAC name

N-(46-dimethylpyrimidin-2-yl)-4-({4-[4-(propan-2-yl)phenyl]-13-thiazol-2-yl}amino)benzene-1-sulfonamide

SMILES

CC(C)c(cc1)ccc1-c1csc(Nc(cc2)ccc2S(Nc2nc(C)cc(C)n2)(=O)=O)n1

InChI

InChI=1S/C24H25N5O2S2/c1-15(2)18-5-7-19(8-6-18)22-14-32-24(28-22)27-20-9-11-21(12-10-20)33(30,31)29-23-25-16(3)13-17(4)26-23/h5-15H,1-4H3,(H,27,28)(H,25,26,29)

InChI Key

FPTFXAIGPHUIBV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03542405

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.63

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.142

Distribution Coefficient, logD

5.660

Water Solubility, LogSw

-5.64

Polar Surface Area

78.894

Acid Dissociation Constant (pKa)

7.09

Base Dissociation Constant (pKb)

3.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

5186-0144 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 5186-0144 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5186-0144?
Check Price and Availability of 5186-0144, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5186-0144 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5186-0144
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5186-0144
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5186-0144 available by request