5186-0275 Screening compound: N4-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]-N1,N1-dimethylbenzene-1,4-diamine

5186-0275 Screening compound: N4-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]-N1,N1-dimethylbenzene-1,4-diamine
5186-0275 Screening compound: N4-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]-N1,N1-dimethylbenzene-1,4-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound 5186-0275
N4-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]-N1,N1-dimethylbenzene-1,4-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5186-0275

Molecular Formula

C18H18FN3S (C18 H18 FN3 S)

Compound Name

N4-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]-N1,N1-dimethylbenzene-1,4-diamine

IUPAC name

N4-[4-(4-fluoro-3-methylphenyl)-13-thiazol-2-yl]-N1N1-dimethylbenzene-14-diamine

SMILES

Cc(cc(cc1)-c2csc(Nc(cc3)ccc3N(C)C)n2)c1F

InChI

InChI=1S/C18H18FN3S/c1-12-10-13(4-9-16(12)19)17-11-23-18(21-17)20-14-5-7-15(8-6-14)22(2)3/h4-11H,1-3H3,(H,20,21)

InChI Key

JFOWDXGZVWZIMK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03542518

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

327.43

Hydrogen Bond Acceptors Count

1.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.709

Distribution Coefficient, logD

5.698

Water Solubility, LogSw

-5.61

Polar Surface Area

21.730

Acid Dissociation Constant (pKa)

20.49

Base Dissociation Constant (pKb)

9.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

5186-0275 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Proteases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 5186-0275 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5186-0275?
Check Price and Availability of 5186-0275, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5186-0275 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5186-0275
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5186-0275
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5186-0275 available by request