5186-0292 Screening compound: N-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]-6-methylpyridin-2-amine

5186-0292 Screening compound: N-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]-6-methylpyridin-2-amine
5186-0292 Screening compound: N-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]-6-methylpyridin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 5186-0292
N-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]-6-methylpyridin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5186-0292

Molecular Formula

C16H14FN3S (C16 H14 FN3 S)

Compound Name

N-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]-6-methylpyridin-2-amine

IUPAC name

N-[4-(4-fluoro-3-methylphenyl)-13-thiazol-2-yl]-6-methylpyridin-2-amine

SMILES

Cc(cc(cc1)-c2csc(Nc3nc(C)ccc3)n2)c1F

InChI

InChI=1S/C16H14FN3S/c1-10-8-12(6-7-13(10)17)14-9-21-16(19-14)20-15-5-3-4-11(2)18-15/h3-9H,1-2H3,(H,18,19,20)

InChI Key

KOUHBYHVJLBJNC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03448570

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

299.37

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.372

Distribution Coefficient, logD

5.309

Water Solubility, LogSw

-5.67

Polar Surface Area

27.915

Acid Dissociation Constant (pKa)

18.94

Base Dissociation Constant (pKb)

6.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

5186-0292 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antiviral Annotated Library (21441 compounds)

CNS targets activity set (6557 compounds)

Human Receptors Annotated Library (5376 compounds)

SmartTM Library (51161 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 5186-0292 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5186-0292?
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What is the minimum amount of 5186-0292 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5186-0292
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5186-0292
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5186-0292 available by request