5225-5926 Screening compound: N,7-bis(2-methoxyphenyl)-5-methyl-2-(thiophen-2-yl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide

5225-5926 Screening compound: N,7-bis(2-methoxyphenyl)-5-methyl-2-(thiophen-2-yl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
5225-5926 Screening compound: N,7-bis(2-methoxyphenyl)-5-methyl-2-(thiophen-2-yl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 5225-5926
N,7-bis(2-methoxyphenyl)-5-methyl-2-(thiophen-2-yl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5225-5926

Molecular Formula

C25H23N5O3S (C25 H23 N5 O3 S)

Compound Name

N,7-bis(2-methoxyphenyl)-5-methyl-2-(thiophen-2-yl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide

IUPAC name

N7-bis(2-methoxyphenyl)-5-methyl-2-(thiophen-2-yl)-4H7H-[124]triazolo[15-a]pyrimidine-6-carboxamide

SMILES

CC(Nc1nc(-c2cccs2)nn1C1c(cccc2)c2OC)=C1C(Nc(cccc1)c1OC)=O

InChI

InChI=1S/C25H23N5O3S/c1-15-21(24(31)27-17-10-5-7-12-19(17)33-3)22(16-9-4-6-11-18(16)32-2)30-25(26-15)28-23(29-30)20-13-8-14-34-20/h4-14,22H,1-3H3,(H,27,31)(H,26,28,29)/t22-/m0/s1

InChI Key

QTDDDVIAOJBOKO-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD05716677

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

473.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.001

Distribution Coefficient, logD

5.001

Water Solubility, LogSw

-4.66

Polar Surface Area

75.450

Acid Dissociation Constant (pKa)

11.08

Base Dissociation Constant (pKb)

3.50

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.00

5225-5926 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 5225-5926 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5225-5926?
Check Price and Availability of 5225-5926, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5225-5926 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5225-5926
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5225-5926
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5225-5926 available by request