5267-1630 Screening compound: 6-chloro-4-phenyl-3-[(2E)-3-(pyridin-3-yl)prop-2-enoyl]-1,2-dihydroquinolin-2-one

5267-1630 Screening compound: 6-chloro-4-phenyl-3-[(2E)-3-(pyridin-3-yl)prop-2-enoyl]-1,2-dihydroquinolin-2-one
5267-1630 Screening compound: 6-chloro-4-phenyl-3-[(2E)-3-(pyridin-3-yl)prop-2-enoyl]-1,2-dihydroquinolin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 5267-1630
6-chloro-4-phenyl-3-[(2E)-3-(pyridin-3-yl)prop-2-enoyl]-1,2-dihydroquinolin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5267-1630

Molecular Formula

C23H15ClN2O2 (C23 H15 ClN2 O2)

Compound Name

6-chloro-4-phenyl-3-[(2E)-3-(pyridin-3-yl)prop-2-enoyl]-1,2-dihydroquinolin-2-one

IUPAC name

6-chloro-4-phenyl-3-[(2E)-3-(pyridin-3-yl)prop-2-enoyl]-12-dihydroquinolin-2-one

SMILES

O=C(/C=C/c1cnccc1)C1=C(c2ccccc2)c(cc(cc2)Cl)c2NC1=O

InChI

InChI=1S/C23H15ClN2O2/c24-17-9-10-19-18(13-17)21(16-6-2-1-3-7-16)22(23(28)26-19)20(27)11-8-15-5-4-12-25-14-15/h1-14H,(H,26,28)

InChI Key

UTIWQCCMBJPWLT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02048508

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.84

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.365

Distribution Coefficient, logD

3.351

Water Solubility, LogSw

-4.71

Polar Surface Area

47.338

Acid Dissociation Constant (pKa)

6.43

Base Dissociation Constant (pKb)

0.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

5267-1630 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 5267-1630 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5267-1630?
Check Price and Availability of 5267-1630, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5267-1630 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5267-1630
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5267-1630
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5267-1630 available by request