5353-0782 Screening compound: 3-hydroxy-1-methyl-3-[2-oxo-2-(pyridin-2-yl)ethyl]-2,3-dihydro-1H-indol-2-one

5353-0782 Screening compound: 3-hydroxy-1-methyl-3-[2-oxo-2-(pyridin-2-yl)ethyl]-2,3-dihydro-1H-indol-2-one
5353-0782 Screening compound: 3-hydroxy-1-methyl-3-[2-oxo-2-(pyridin-2-yl)ethyl]-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 5353-0782
3-hydroxy-1-methyl-3-[2-oxo-2-(pyridin-2-yl)ethyl]-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5353-0782

Molecular Formula

C16H14N2O3 (C16 H14 N2 O3)

Compound Name

3-hydroxy-1-methyl-3-[2-oxo-2-(pyridin-2-yl)ethyl]-2,3-dihydro-1H-indol-2-one

IUPAC name

n/a

SMILES

CN(C(C1(CC(c2ncccc2)=O)O)=O)c2c1cccc2

InChI

InChI=1S/C16H14N2O3/c1-18-13-8-3-2-6-11(13)16(21,15(18)20)10-14(19)12-7-4-5-9-17-12/h2-9,21H,10H2,1H3/t16-/m0/s1

InChI Key

AXONVSGLFJYKHU-INIZCTEOSA-N

MDL Number (MFCD)

MFCD01416299

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

282.3

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

0.835

Distribution Coefficient, logD

0.835

Water Solubility, LogSw

-1.94

Polar Surface Area

53.128

Acid Dissociation Constant (pKa)

14.32

Base Dissociation Constant (pKb)

0.78

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

18.80

5353-0782 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 5353-0782 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5353-0782?
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What is the minimum amount of 5353-0782 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5353-0782
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5353-0782
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5353-0782 available by request