5353-0873 Screening compound: 5-bromo-3-hydroxy-3-[2-(3-methoxyphenyl)-2-oxoethyl]-2,3-dihydro-1H-indol-2-one

5353-0873 Screening compound: 5-bromo-3-hydroxy-3-[2-(3-methoxyphenyl)-2-oxoethyl]-2,3-dihydro-1H-indol-2-one
5353-0873 Screening compound: 5-bromo-3-hydroxy-3-[2-(3-methoxyphenyl)-2-oxoethyl]-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 5353-0873
5-bromo-3-hydroxy-3-[2-(3-methoxyphenyl)-2-oxoethyl]-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5353-0873

Molecular Formula

C17H14BrNO4 (C17 H14 BrNO4)

Compound Name

5-bromo-3-hydroxy-3-[2-(3-methoxyphenyl)-2-oxoethyl]-2,3-dihydro-1H-indol-2-one

IUPAC name

5-bromo-3-hydroxy-3-[2-(3-methoxyphenyl)-2-oxoethyl]-23-dihydro-1H-indol-2-one

SMILES

COc1cccc(C(CC(c(cc(cc2)Br)c2N2)(C2=O)O)=O)c1

InChI

InChI=1S/C17H14BrNO4/c1-23-12-4-2-3-10(7-12)15(20)9-17(22)13-8-11(18)5-6-14(13)19-16(17)21/h2-8,22H,9H2,1H3,(H,19,21)/t17-/m0/s1

InChI Key

IKFMJNOEASPXEJ-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD03662039

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.21

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.944

Distribution Coefficient, logD

2.942

Water Solubility, LogSw

-3.56

Polar Surface Area

61.361

Acid Dissociation Constant (pKa)

9.74

Base Dissociation Constant (pKb)

-2.51

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

17.60

5353-0873 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

Cardiovascular Library (22201 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 5353-0873 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5353-0873?
Check Price and Availability of 5353-0873, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5353-0873 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5353-0873
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5353-0873
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5353-0873 available by request