5408-2844 Screening compound: 4-{3-[(E)-[(5-bromo-2-hydroxyphenyl)methylidene]amino]-7-methylimidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol

5408-2844 Screening compound: 4-{3-[(E)-[(5-bromo-2-hydroxyphenyl)methylidene]amino]-7-methylimidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol
5408-2844 Screening compound: 4-{3-[(E)-[(5-bromo-2-hydroxyphenyl)methylidene]amino]-7-methylimidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol alternative view

Chemical Structure Depiction of ChemDiv screening compound 5408-2844
4-{3-[(E)-[(5-bromo-2-hydroxyphenyl)methylidene]amino]-7-methylimidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5408-2844

Molecular Formula

C22H18BrN3O3 (C22 H18 BrN3 O3)

Compound Name

4-{3-[(E)-[(5-bromo-2-hydroxyphenyl)methylidene]amino]-7-methylimidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol

IUPAC name

4-{3-[(E)-[(5-bromo-2-hydroxyphenyl)methylidene]amino]-7-methylimidazo[12-a]pyridin-2-yl}-2-methoxyphenol

SMILES

Cc(ccn12)cc2nc(-c(cc2)cc(OC)c2O)c1/N=C/c(cc(cc1)Br)c1O

InChI

InChI=1S/C22H18BrN3O3/c1-13-7-8-26-20(9-13)25-21(14-3-5-18(28)19(11-14)29-2)22(26)24-12-15-10-16(23)4-6-17(15)27/h3-12,27-28H,1-2H3

InChI Key

MCLMRFSDDQCYKG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03013510

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.31

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.757

Distribution Coefficient, logD

4.742

Water Solubility, LogSw

-4.27

Polar Surface Area

57.621

Acid Dissociation Constant (pKa)

8.98

Base Dissociation Constant (pKb)

5.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

5408-2844 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

BRD4 Targeted Library (4534 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Kinases Annotated Library (2415 compounds)

Covalent Inhibitors Library (7986 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
Targets:
  • Others
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with 5408-2844 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5408-2844?
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What is the minimum amount of 5408-2844 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5408-2844
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5408-2844
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5408-2844 available by request