5458-1572 Screening compound: 3-(2-chloro-6-fluorophenyl)-N-(2-methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide

5458-1572 Screening compound: 3-(2-chloro-6-fluorophenyl)-N-(2-methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide
5458-1572 Screening compound: 3-(2-chloro-6-fluorophenyl)-N-(2-methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 5458-1572
3-(2-chloro-6-fluorophenyl)-N-(2-methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5458-1572

Molecular Formula

C18H14ClFN2O3 (C18 H14 ClFN2 O3)

Compound Name

3-(2-chloro-6-fluorophenyl)-N-(2-methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide

IUPAC name

3-(2-chloro-6-fluorophenyl)-N-(2-methoxyphenyl)-5-methyl-12-oxazole-4-carboxamide

SMILES

Cc1c(C(Nc(cccc2)c2OC)=O)c(-c(c(F)ccc2)c2Cl)no1

InChI

InChI=1S/C18H14ClFN2O3/c1-10-15(18(23)21-13-8-3-4-9-14(13)24-2)17(22-25-10)16-11(19)6-5-7-12(16)20/h3-9H,1-2H3,(H,21,23)

InChI Key

BDTSPGQZCILMJH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00860031

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.77

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.740

Distribution Coefficient, logD

3.718

Water Solubility, LogSw

-4.69

Polar Surface Area

52.222

Acid Dissociation Constant (pKa)

8.68

Base Dissociation Constant (pKb)

-1.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

5458-1572 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-infective Library (19449 compounds)

Antifungal Library (16415 compounds)

Lipid Metabolism Library (9174 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Immune system
  • animal
  • Infections
  • Immune system
  • animal
  • Cardiovascular
  • Metabolic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Agro:
  • Agro
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with 5458-1572 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5458-1572?
Check Price and Availability of 5458-1572, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5458-1572 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5458-1572
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5458-1572
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5458-1572 available by request