5482-0112 Screening compound: 3'-(4-chlorophenyl)-5'-methyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione

5482-0112 Screening compound: 3'-(4-chlorophenyl)-5'-methyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione
5482-0112 Screening compound: 3'-(4-chlorophenyl)-5'-methyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 5482-0112
3'-(4-chlorophenyl)-5'-methyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5482-0112

Molecular Formula

C17H13ClN2O2S (C17 H13 ClN2 O2 S)

Compound Name

3'-(4-chlorophenyl)-5'-methyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione

IUPAC name

3'-(4-chlorophenyl)-5'-methyl-12-dihydrospiro[indole-32'-[13]thiazolidine]-24'-dione

SMILES

CC(C1=O)SC(c(cccc2)c2N2)(C2=O)N1c(cc1)ccc1Cl

InChI

InChI=1S/C17H13ClN2O2S/c1-10-15(21)20(12-8-6-11(18)7-9-12)17(23-10)13-4-2-3-5-14(13)19-16(17)22/h2-10H,1H3,(H,19,22)

InChI Key

SBTSMFZVFMPYRL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00763850

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

344.82

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.609

Distribution Coefficient, logD

3.609

Water Solubility, LogSw

-4.08

Polar Surface Area

40.533

Acid Dissociation Constant (pKa)

11.24

Base Dissociation Constant (pKb)

-2.67

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

17.60

5482-0112 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Antiparasite Library (23996 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Agro:
  • Agro
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with 5482-0112 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5482-0112?
Check Price and Availability of 5482-0112, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5482-0112 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5482-0112
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5482-0112
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5482-0112 available by request