5499-0275 Screening compound: (5Z)-5-[(furan-2-yl)methylidene]-2-[(4-methoxyphenyl)amino]-4,5-dihydro-1,3-thiazol-4-one

5499-0275 Screening compound: (5Z)-5-[(furan-2-yl)methylidene]-2-[(4-methoxyphenyl)amino]-4,5-dihydro-1,3-thiazol-4-one
5499-0275 Screening compound: (5Z)-5-[(furan-2-yl)methylidene]-2-[(4-methoxyphenyl)amino]-4,5-dihydro-1,3-thiazol-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 5499-0275
(5Z)-5-[(furan-2-yl)methylidene]-2-[(4-methoxyphenyl)amino]-4,5-dihydro-1,3-thiazol-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5499-0275

Molecular Formula

C15H12N2O3S (C15 H12 N2 O3 S)

Compound Name

(5Z)-5-[(furan-2-yl)methylidene]-2-[(4-methoxyphenyl)amino]-4,5-dihydro-1,3-thiazol-4-one

IUPAC name

(5Z)-5-[(furan-2-yl)methylidene]-2-[(4-methoxyphenyl)amino]-45-dihydro-13-thiazol-4-one

SMILES

COc(cc1)ccc1NC(S/C1=C\c2ccco2)=NC1=O

InChI

InChI=1S/C15H12N2O3S/c1-19-11-6-4-10(5-7-11)16-15-17-14(18)13(21-15)9-12-3-2-8-20-12/h2-9H,1H3,(H,16,17,18)

InChI Key

KGSRWXSYHTYCIB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03670911

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

300.34

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.968

Distribution Coefficient, logD

2.968

Water Solubility, LogSw

-3.65

Polar Surface Area

46.917

Acid Dissociation Constant (pKa)

10.57

Base Dissociation Constant (pKb)

1.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.70

5499-0275 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with 5499-0275 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5499-0275?
Check Price and Availability of 5499-0275, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5499-0275 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5499-0275
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5499-0275
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5499-0275 available by request