5742-0848 Screening compound: 6-chloro-3-[4-(2-furylcarbonyl)piperazino]-4-phenyl-2(1H)-quinolinone

5742-0848 Screening compound: 6-chloro-3-[4-(2-furylcarbonyl)piperazino]-4-phenyl-2(1H)-quinolinone
5742-0848 Screening compound: 6-chloro-3-[4-(2-furylcarbonyl)piperazino]-4-phenyl-2(1H)-quinolinone alternative view

Chemical Structure Depiction of ChemDiv screening compound 5742-0848
6-chloro-3-[4-(2-furylcarbonyl)piperazino]-4-phenyl-2(1H)-quinolinone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5742-0848

Molecular Formula

C24H20ClN3O3 (C24 H20 ClN3 O3)

Compound Name

6-chloro-3-[4-(2-furylcarbonyl)piperazino]-4-phenyl-2(1H)-quinolinone

IUPAC name

n/a

SMILES

O=C(c1ccco1)N(CC1)CCN1C1=C(c2ccccc2)c(cc(cc2)Cl)c2NC1=O

InChI

InChI=1S/C24H20ClN3O3/c25-17-8-9-19-18(15-17)21(16-5-2-1-3-6-16)22(23(29)26-19)27-10-12-28(13-11-27)24(30)20-7-4-14-31-20/h1-9,14-15H,10-13H2,(H,26,29)

InChI Key

NJEYJUSQLNNSFM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03612771

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.89

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.282

Distribution Coefficient, logD

4.193

Water Solubility, LogSw

-4.54

Polar Surface Area

53.250

Acid Dissociation Constant (pKa)

8.04

Base Dissociation Constant (pKb)

3.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

5742-0848 in Drug Discovery

Included in Screening Libraries

CNS targets activity set (6557 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 5742-0848 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5742-0848?
Check Price and Availability of 5742-0848, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5742-0848 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5742-0848
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5742-0848
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5742-0848 available by request