6049-1785 Screening compound: (2E)-3-(3,4-dimethoxyphenyl)-N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}prop-2-enamide

6049-1785 Screening compound: (2E)-3-(3,4-dimethoxyphenyl)-N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}prop-2-enamide
6049-1785 Screening compound: (2E)-3-(3,4-dimethoxyphenyl)-N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6049-1785
(2E)-3-(3,4-dimethoxyphenyl)-N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6049-1785

Molecular Formula

C22H23N3O6S (C22 H23 N3 O6 S)

Compound Name

(2E)-3-(3,4-dimethoxyphenyl)-N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}prop-2-enamide

IUPAC name

(2E)-3-(34-dimethoxyphenyl)-N-{4-[(34-dimethyl-12-oxazol-5-yl)sulfamoyl]phenyl}prop-2-enamide

SMILES

Cc1c(NS(c(cc2)ccc2NC(/C=C/c(cc2)cc(OC)c2OC)=O)(=O)=O)onc1C

InChI

InChI=1S/C22H23N3O6S/c1-14-15(2)24-31-22(14)25-32(27,28)18-9-7-17(8-10-18)23-21(26)12-6-16-5-11-19(29-3)20(13-16)30-4/h5-13,25H,1-4H3,(H,23,26)

InChI Key

IAZZJOSRGOLSOP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03390532

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.51

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.173

Distribution Coefficient, logD

1.163

Water Solubility, LogSw

-3.64

Polar Surface Area

101.691

Acid Dissociation Constant (pKa)

5.40

Base Dissociation Constant (pKb)

-0.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

6049-1785 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

KRAS-Targeted Library (16000 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with 6049-1785 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6049-1785?
Check Price and Availability of 6049-1785, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6049-1785 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6049-1785
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6049-1785
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6049-1785 available by request