6144-0577 Screening compound: N-(4-methylphenyl)-4-(quinoline-8-sulfonamido)benzamide

6144-0577 Screening compound: N-(4-methylphenyl)-4-(quinoline-8-sulfonamido)benzamide
6144-0577 Screening compound: N-(4-methylphenyl)-4-(quinoline-8-sulfonamido)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6144-0577
N-(4-methylphenyl)-4-(quinoline-8-sulfonamido)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6144-0577

Molecular Formula

C23H19N3O3S (C23 H19 N3 O3 S)

Compound Name

N-(4-methylphenyl)-4-(quinoline-8-sulfonamido)benzamide

IUPAC name

N-(4-methylphenyl)-4-(quinoline-8-sulfonamido)benzamide

SMILES

Cc(cc1)ccc1NC(c(cc1)ccc1NS(c1cccc2cccnc12)(=O)=O)=O

InChI

InChI=1S/C23H19N3O3S/c1-16-7-11-19(12-8-16)25-23(27)18-9-13-20(14-10-18)26-30(28,29)21-6-2-4-17-5-3-15-24-22(17)21/h2-15,26H,1H3,(H,25,27)

InChI Key

ZVUGFODEAXZKBX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05717293

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.866

Distribution Coefficient, logD

2.172

Water Solubility, LogSw

-3.72

Polar Surface Area

73.512

Acid Dissociation Constant (pKa)

5.71

Base Dissociation Constant (pKb)

0.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

6144-0577 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Autophagy-Targeted Library (4564 compounds)

CNS targets activity set (6557 compounds)

Dark Chemical Matter Library (18430 compounds)

Glucocorticoid receptors Library (4806 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Pool
Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 6144-0577 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6144-0577?
Check Price and Availability of 6144-0577, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6144-0577 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6144-0577
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6144-0577
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6144-0577 available by request