6145-0517 Screening compound: 4-ethyl-N~1~-(3-methyl-2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinolin-6-yl)-1-benzenesulfonamide

6145-0517 Screening compound: 4-ethyl-N~1~-(3-methyl-2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinolin-6-yl)-1-benzenesulfonamide
6145-0517 Screening compound: 4-ethyl-N~1~-(3-methyl-2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinolin-6-yl)-1-benzenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6145-0517
4-ethyl-N~1~-(3-methyl-2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinolin-6-yl)-1-benzenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6145-0517

Molecular Formula

C25H20N2O4S (C25 H20 N2 O4 S)

Compound Name

4-ethyl-N~1~-(3-methyl-2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinolin-6-yl)-1-benzenesulfonamide

IUPAC name

4-ethyl-N-{14-methyl-815-dioxo-14-azatetracyclo[7.7.1.0^{27}.0^{1317}]heptadeca-1(16)2469(17)1012-heptaen-10-yl}benzene-1-sulfonamide

SMILES

CCc(cc1)ccc1S(Nc(ccc(N1C)c2C(c3c4cccc3)=CC1=O)c2C4=O)(=O)=O

InChI

InChI=1S/C25H20N2O4S/c1-3-15-8-10-16(11-9-15)32(30,31)26-20-12-13-21-23-19(14-22(28)27(21)2)17-6-4-5-7-18(17)25(29)24(20)23/h4-14,26H,3H2,1-2H3

InChI Key

UNICSFNMNHZASF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06249800

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.403

Distribution Coefficient, logD

3.860

Water Solubility, LogSw

-4.46

Polar Surface Area

68.403

Acid Dissociation Constant (pKa)

7.00

Base Dissociation Constant (pKb)

-7.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

6145-0517 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with 6145-0517 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6145-0517?
Check Price and Availability of 6145-0517, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6145-0517 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6145-0517
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6145-0517
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6145-0517 available by request