6149-0135 Screening compound: N-{5-[(2-chlorophenyl)methyl]-1,3-thiazol-2-yl}-2-phenylquinoline-4-carboxamide

6149-0135 Screening compound: N-{5-[(2-chlorophenyl)methyl]-1,3-thiazol-2-yl}-2-phenylquinoline-4-carboxamide
6149-0135 Screening compound: N-{5-[(2-chlorophenyl)methyl]-1,3-thiazol-2-yl}-2-phenylquinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6149-0135
N-{5-[(2-chlorophenyl)methyl]-1,3-thiazol-2-yl}-2-phenylquinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6149-0135

Molecular Formula

C26H18ClN3OS (C26 H18 ClN3 OS)

Compound Name

N-{5-[(2-chlorophenyl)methyl]-1,3-thiazol-2-yl}-2-phenylquinoline-4-carboxamide

IUPAC name

N-{5-[(2-chlorophenyl)methyl]-13-thiazol-2-yl}-2-phenylquinoline-4-carboxamide

SMILES

O=C(c1cc(-c2ccccc2)nc2ccccc12)Nc1ncc(Cc(cccc2)c2Cl)s1

InChI

InChI=1S/C26H18ClN3OS/c27-22-12-6-4-10-18(22)14-19-16-28-26(32-19)30-25(31)21-15-24(17-8-2-1-3-9-17)29-23-13-7-5-11-20(21)23/h1-13,15-16H,14H2,(H,28,30,31)

InChI Key

JIMWSFZRZUCNLW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04159728

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.97

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

7.646

Distribution Coefficient, logD

7.645

Water Solubility, LogSw

-6.61

Polar Surface Area

41.685

Acid Dissociation Constant (pKa)

10.02

Base Dissociation Constant (pKb)

1.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

3.80

6149-0135 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 6149-0135 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6149-0135?
Check Price and Availability of 6149-0135, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6149-0135 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6149-0135
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6149-0135
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6149-0135 available by request