6186-3466 Screening compound: 2-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]-1,2-diphenylethan-1-one

6186-3466 Screening compound: 2-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]-1,2-diphenylethan-1-one
6186-3466 Screening compound: 2-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]-1,2-diphenylethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 6186-3466
2-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]-1,2-diphenylethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6186-3466

Molecular Formula

C24H20N2O2S (C24 H20 N2 O2 S)

Compound Name

2-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]-1,2-diphenylethan-1-one

IUPAC name

2-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]-12-diphenylethan-1-one

SMILES

Cc(c1c2)nc(SC(C(c3ccccc3)=O)c3ccccc3)nc1ccc2OC

InChI

InChI=1S/C24H20N2O2S/c1-16-20-15-19(28-2)13-14-21(20)26-24(25-16)29-23(18-11-7-4-8-12-18)22(27)17-9-5-3-6-10-17/h3-15,23H,1-2H3/t23-/m1/s1

InChI Key

WEEQPHOLZOBUNO-HSZRJFAPSA-N

MDL Number (MFCD)

MFCD03302940

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.031

Distribution Coefficient, logD

6.031

Water Solubility, LogSw

-5.68

Polar Surface Area

38.563

Acid Dissociation Constant (pKa)

11.08

Base Dissociation Constant (pKb)

1.98

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.50

6186-3466 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

CNS targets activity set (6557 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 6186-3466 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6186-3466?
Check Price and Availability of 6186-3466, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6186-3466 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6186-3466
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6186-3466
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6186-3466 available by request