6186-3691 Screening compound: 1-(10H-phenothiazin-10-yl)-2-[(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)oxy]ethan-1-one

6186-3691 Screening compound: 1-(10H-phenothiazin-10-yl)-2-[(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)oxy]ethan-1-one
6186-3691 Screening compound: 1-(10H-phenothiazin-10-yl)-2-[(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)oxy]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 6186-3691
1-(10H-phenothiazin-10-yl)-2-[(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)oxy]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6186-3691

Molecular Formula

C26H24N2O2S (C26 H24 N2 O2 S)

Compound Name

1-(10H-phenothiazin-10-yl)-2-[(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)oxy]ethan-1-one

IUPAC name

1-(10H-phenothiazin-10-yl)-2-[(224-trimethyl-12-dihydroquinolin-6-yl)oxy]ethan-1-one

SMILES

CC1(C)Nc(ccc(OCC(N2c(cccc3)c3Sc3c2cccc3)=O)c2)c2C(C)=C1

InChI

InChI=1S/C26H24N2O2S/c1-17-15-26(2,3)27-20-13-12-18(14-19(17)20)30-16-25(29)28-21-8-4-6-10-23(21)31-24-11-7-5-9-22(24)28/h4-15,27H,16H2,1-3H3

InChI Key

ARCYMJUTUSEOAN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03488103

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.716

Distribution Coefficient, logD

5.716

Water Solubility, LogSw

-5.43

Polar Surface Area

32.040

Acid Dissociation Constant (pKa)

18.06

Base Dissociation Constant (pKb)

7.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

6186-3691 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

KRAS-Targeted Library (16000 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 6186-3691 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6186-3691?
Check Price and Availability of 6186-3691, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6186-3691 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6186-3691
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6186-3691
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6186-3691 available by request