6193-1022 Screening compound: (5Z)-2-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino]-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-4,5-dihydro-1,3-thiazol-4-one

6193-1022 Screening compound: (5Z)-2-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino]-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-4,5-dihydro-1,3-thiazol-4-one
6193-1022 Screening compound: (5Z)-2-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino]-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-4,5-dihydro-1,3-thiazol-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 6193-1022
(5Z)-2-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino]-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-4,5-dihydro-1,3-thiazol-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6193-1022

Molecular Formula

C22H20N4O4S (C22 H20 N4 O4 S)

Compound Name

(5Z)-2-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino]-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-4,5-dihydro-1,3-thiazol-4-one

IUPAC name

(5Z)-2-[(15-dimethyl-3-oxo-2-phenyl-23-dihydro-1H-pyrazol-4-yl)amino]-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-45-dihydro-13-thiazol-4-one

SMILES

CC(N(C)N(C1=O)c2ccccc2)=C1NC(S/C1=C\c(cc2)cc(OC)c2O)=NC1=O

InChI

InChI=1S/C22H20N4O4S/c1-13-19(21(29)26(25(13)2)15-7-5-4-6-8-15)23-22-24-20(28)18(31-22)12-14-9-10-16(27)17(11-14)30-3/h4-12,27H,1-3H3,(H,23,24,28)

InChI Key

RKUZKQLXNHPGSY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04441071

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.519

Distribution Coefficient, logD

0.645

Water Solubility, LogSw

-2.21

Polar Surface Area

76.184

Acid Dissociation Constant (pKa)

6.59

Base Dissociation Constant (pKb)

1.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

6193-1022 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with 6193-1022 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6193-1022?
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What is the minimum amount of 6193-1022 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6193-1022
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6193-1022
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6193-1022 available by request