6219-0033 Screening compound: N-(4-{[5-(4-chlorophenyl)-7-(2-methoxyphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]sulfamoyl}phenyl)acetamide

6219-0033 Screening compound: N-(4-{[5-(4-chlorophenyl)-7-(2-methoxyphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]sulfamoyl}phenyl)acetamide
6219-0033 Screening compound: N-(4-{[5-(4-chlorophenyl)-7-(2-methoxyphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]sulfamoyl}phenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6219-0033
N-(4-{[5-(4-chlorophenyl)-7-(2-methoxyphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]sulfamoyl}phenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6219-0033

Molecular Formula

C26H23ClN6O4S (C26 H23 ClN6 O4 S)

Compound Name

N-(4-{[5-(4-chlorophenyl)-7-(2-methoxyphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]sulfamoyl}phenyl)acetamide

IUPAC name

N-(4-{[5-(4-chlorophenyl)-7-(2-methoxyphenyl)-4H7H-[124]triazolo[15-a]pyrimidin-2-yl]sulfamoyl}phenyl)acetamide

SMILES

CC(Nc(cc1)ccc1S(Nc1nn(C(C=C(c(cc2)ccc2Cl)N2)c(cccc3)c3OC)c2n1)(=O)=O)=O

InChI

InChI=1S/C26H23ClN6O4S/c1-16(34)28-19-11-13-20(14-12-19)38(35,36)32-25-30-26-29-22(17-7-9-18(27)10-8-17)15-23(33(26)31-25)21-5-3-4-6-24(21)37-2/h3-15,23H,1-2H3,(H,28,34)(H2,29,30,31,32)/t23-/m1/s1

InChI Key

FQTGLOFBRWLYCJ-HSZRJFAPSA-N

MDL Number (MFCD)

MFCD04213083

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

551.03

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

4.725

Distribution Coefficient, logD

4.216

Water Solubility, LogSw

-4.94

Polar Surface Area

110.335

Acid Dissociation Constant (pKa)

7.05

Base Dissociation Constant (pKb)

-1.54

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

11.50

6219-0033 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 6219-0033 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6219-0033?
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What is the minimum amount of 6219-0033 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6219-0033
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6219-0033
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6219-0033 available by request