6220-2179 Screening compound: 5-[1,3-bis(4-methylphenyl)imidazolidin-2-yl]-2-methoxyphenol

6220-2179 Screening compound: 5-[1,3-bis(4-methylphenyl)imidazolidin-2-yl]-2-methoxyphenol
6220-2179 Screening compound: 5-[1,3-bis(4-methylphenyl)imidazolidin-2-yl]-2-methoxyphenol alternative view

Chemical Structure Depiction of ChemDiv screening compound 6220-2179
5-[1,3-bis(4-methylphenyl)imidazolidin-2-yl]-2-methoxyphenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6220-2179

Molecular Formula

C24H26N2O2 (C24 H26 N2 O2)

Compound Name

5-[1,3-bis(4-methylphenyl)imidazolidin-2-yl]-2-methoxyphenol

IUPAC name

5-[13-bis(4-methylphenyl)imidazolidin-2-yl]-2-methoxyphenol

SMILES

Cc(cc1)ccc1N(CC1)C(c(cc2)cc(O)c2OC)N1c1ccc(C)cc1

InChI

InChI=1S/C24H26N2O2/c1-17-4-9-20(10-5-17)25-14-15-26(21-11-6-18(2)7-12-21)24(25)19-8-13-23(28-3)22(27)16-19/h4-13,16,24,27H,14-15H2,1-3H3

InChI Key

AWVYJNXLDXXMLX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00596725

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.48

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.390

Distribution Coefficient, logD

5.376

Water Solubility, LogSw

-5.28

Polar Surface Area

30.365

Acid Dissociation Constant (pKa)

8.89

Base Dissociation Constant (pKb)

2.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

6220-2179 in Drug Discovery

Included in Screening Libraries

CNS targets activity set (6557 compounds)

Glucocorticoid receptors Library (4806 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with 6220-2179 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6220-2179?
Check Price and Availability of 6220-2179, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6220-2179 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6220-2179
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6220-2179
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6220-2179 available by request