6434-3642 Screening compound: 2-(4-methylphenoxy)-1-[4-(4-phenylphthalazin-1-yl)piperazin-1-yl]ethan-1-one

6434-3642 Screening compound: 2-(4-methylphenoxy)-1-[4-(4-phenylphthalazin-1-yl)piperazin-1-yl]ethan-1-one
6434-3642 Screening compound: 2-(4-methylphenoxy)-1-[4-(4-phenylphthalazin-1-yl)piperazin-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 6434-3642
2-(4-methylphenoxy)-1-[4-(4-phenylphthalazin-1-yl)piperazin-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6434-3642

Molecular Formula

C27H26N4O2 (C27 H26 N4 O2)

Compound Name

2-(4-methylphenoxy)-1-[4-(4-phenylphthalazin-1-yl)piperazin-1-yl]ethan-1-one

IUPAC name

2-(4-methylphenoxy)-1-[4-(4-phenylphthalazin-1-yl)piperazin-1-yl]ethan-1-one

SMILES

Cc(cc1)ccc1OCC(N(CC1)CCN1c1nnc(-c2ccccc2)c2ccccc12)=O

InChI

InChI=1S/C27H26N4O2/c1-20-11-13-22(14-12-20)33-19-25(32)30-15-17-31(18-16-30)27-24-10-6-5-9-23(24)26(28-29-27)21-7-3-2-4-8-21/h2-14H,15-19H2,1H3

InChI Key

IAPQXANGZKUWPO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04033459

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.377

Distribution Coefficient, logD

4.377

Water Solubility, LogSw

-4.21

Polar Surface Area

49.022

Acid Dissociation Constant (pKa)

24.12

Base Dissociation Constant (pKb)

5.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

6434-3642 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

CNS targets activity set (6557 compounds)

Human Ion Channels Annotated Library (353 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Immune system
Targets:
  • Kinases
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 6434-3642 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6434-3642?
Check Price and Availability of 6434-3642, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6434-3642 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6434-3642
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6434-3642
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6434-3642 available by request