6434-3704 Screening compound: 1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-4-(4-methylphenyl)phthalazine

6434-3704 Screening compound: 1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-4-(4-methylphenyl)phthalazine
6434-3704 Screening compound: 1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-4-(4-methylphenyl)phthalazine alternative view

Chemical Structure Depiction of ChemDiv screening compound 6434-3704
1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-4-(4-methylphenyl)phthalazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6434-3704

Molecular Formula

C25H23FN4O2S (C25 H23 FN4 O2 S)

Compound Name

1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-4-(4-methylphenyl)phthalazine

IUPAC name

1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-4-(4-methylphenyl)phthalazine

SMILES

Cc(cc1)ccc1-c(c1ccccc11)nnc1N(CC1)CCN1S(c(cc1)ccc1F)(=O)=O

InChI

InChI=1S/C25H23FN4O2S/c1-18-6-8-19(9-7-18)24-22-4-2-3-5-23(22)25(28-27-24)29-14-16-30(17-15-29)33(31,32)21-12-10-20(26)11-13-21/h2-13H,14-17H2,1H3

InChI Key

HJGSKKZDFAIAFP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04031599

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.55

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.002

Distribution Coefficient, logD

5.001

Water Solubility, LogSw

-4.79

Polar Surface Area

57.113

Acid Dissociation Constant (pKa)

23.84

Base Dissociation Constant (pKb)

5.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

6434-3704 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 6434-3704 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6434-3704?
Check Price and Availability of 6434-3704, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6434-3704 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6434-3704
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6434-3704
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6434-3704 available by request