6448-0035 Screening compound: 7-(4-methylphenyl)-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine

6448-0035 Screening compound: 7-(4-methylphenyl)-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine
6448-0035 Screening compound: 7-(4-methylphenyl)-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound 6448-0035
7-(4-methylphenyl)-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6448-0035

Molecular Formula

C18H14N4 (C18 H14 N4)

Compound Name

7-(4-methylphenyl)-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine

IUPAC name

7-(4-methylphenyl)-5-phenyl-[124]triazolo[15-a]pyrimidine

SMILES

Cc(cc1)ccc1-c1cc(-c2ccccc2)nc2ncnn12

InChI

InChI=1S/C18H14N4/c1-13-7-9-15(10-8-13)17-11-16(14-5-3-2-4-6-14)21-18-19-12-20-22(17)18/h2-12H,1H3

InChI Key

DHIASPSEHZBTKI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03686125

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

286.34

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.471

Distribution Coefficient, logD

4.471

Water Solubility, LogSw

-4.48

Polar Surface Area

30.450

Acid Dissociation Constant (pKa)

28.80

Base Dissociation Constant (pKb)

2.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

6448-0035 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 6448-0035 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6448-0035?
Check Price and Availability of 6448-0035, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6448-0035 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6448-0035
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6448-0035
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6448-0035 available by request