6466-1016 Screening compound: N-(5-tert-butyl-2-methoxyphenyl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

6466-1016 Screening compound: N-(5-tert-butyl-2-methoxyphenyl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide
6466-1016 Screening compound: N-(5-tert-butyl-2-methoxyphenyl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6466-1016
N-(5-tert-butyl-2-methoxyphenyl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6466-1016

Molecular Formula

C23H25F3N4O3 (C23 H25 F3 N4 O3)

Compound Name

N-(5-tert-butyl-2-methoxyphenyl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

(5R7S)-N-(5-tert-butyl-2-methoxyphenyl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H5H6H7H-pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

CC(C)(C)c(cc1)cc(NC(c2nn([C@H](C[C@@H](c3ccco3)N3)C(F)(F)F)c3c2)=O)c1OC

InChI

InChI=1S/C23H25F3N4O3/c1-22(2,3)13-7-8-17(32-4)14(10-13)28-21(31)16-12-20-27-15(18-6-5-9-33-18)11-19(23(24,25)26)30(20)29-16/h5-10,12,15,19,27H,11H2,1-4H3,(H,28,31)/t15-,19-/m1/s1

InChI Key

OBBZXFKKAORNOT-DNVCBOLYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.263

Distribution Coefficient, logD

5.263

Water Solubility, LogSw

-5.14

Polar Surface Area

66.368

Acid Dissociation Constant (pKa)

11.42

Base Dissociation Constant (pKb)

-0.43

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

39.10

6466-1016 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 6466-1016 chemical compound. It will be published here after verification.

Frequently Asked Questions

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What is the minimum amount of 6466-1016 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6466-1016
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6466-1016
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6466-1016 available by request