6466-1067 Screening compound: N-(1-benzyl-1H-pyrazol-4-yl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

6466-1067 Screening compound: N-(1-benzyl-1H-pyrazol-4-yl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide
6466-1067 Screening compound: N-(1-benzyl-1H-pyrazol-4-yl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6466-1067
N-(1-benzyl-1H-pyrazol-4-yl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6466-1067

Molecular Formula

C22H19F3N6O2 (C22 H19 F3 N6 O2)

Compound Name

N-(1-benzyl-1H-pyrazol-4-yl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

(5R7S)-N-(1-benzyl-1H-pyrazol-4-yl)-5-(furan-2-yl)-7-(trifluoromethyl)-4H5H6H7H-pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

O=C(c1nn([C@H](C[C@@H](c2ccco2)N2)C(F)(F)F)c2c1)Nc1cn(Cc2ccccc2)nc1

InChI

InChI=1S/C22H19F3N6O2/c23-22(24,25)19-9-16(18-7-4-8-33-18)28-20-10-17(29-31(19)20)21(32)27-15-11-26-30(13-15)12-14-5-2-1-3-6-14/h1-8,10-11,13,16,19,28H,9,12H2,(H,27,32)/t16-,19-/m1/s1

InChI Key

KBVCTPHAWGNKEA-VQIMIIECSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.419

Distribution Coefficient, logD

3.419

Water Solubility, LogSw

-3.59

Polar Surface Area

73.941

Acid Dissociation Constant (pKa)

10.70

Base Dissociation Constant (pKb)

-1.50

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

22.70

6466-1067 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 6466-1067 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6466-1067?
Check Price and Availability of 6466-1067, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6466-1067 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6466-1067
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6466-1067
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6466-1067 available by request