6466-1345 Screening compound: 7-(difluoromethyl)-N-{4-[(4-methoxyphenyl)sulfamoyl]phenyl}-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide

6466-1345 Screening compound: 7-(difluoromethyl)-N-{4-[(4-methoxyphenyl)sulfamoyl]phenyl}-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide
6466-1345 Screening compound: 7-(difluoromethyl)-N-{4-[(4-methoxyphenyl)sulfamoyl]phenyl}-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6466-1345
7-(difluoromethyl)-N-{4-[(4-methoxyphenyl)sulfamoyl]phenyl}-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6466-1345

Molecular Formula

C21H18F2N6O4S (C21 H18 F2 N6 O4 S)

Compound Name

7-(difluoromethyl)-N-{4-[(4-methoxyphenyl)sulfamoyl]phenyl}-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

7-(difluoromethyl)-N-{4-[(4-methoxyphenyl)sulfamoyl]phenyl}-5-methyl-[124]triazolo[15-a]pyrimidine-2-carboxamide

SMILES

Cc1nc2nc(C(Nc(cc3)ccc3S(Nc(cc3)ccc3OC)(=O)=O)=O)nn2c(C(F)F)c1

InChI

InChI=1S/C21H18F2N6O4S/c1-12-11-17(18(22)23)29-21(24-12)26-19(27-29)20(30)25-13-5-9-16(10-6-13)34(31,32)28-14-3-7-15(33-2)8-4-14/h3-11,18,28H,1-2H3,(H,25,30)

InChI Key

OHMGSQUENLTRID-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02175793

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.47

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.617

Distribution Coefficient, logD

2.612

Water Solubility, LogSw

-3.28

Polar Surface Area

101.144

Acid Dissociation Constant (pKa)

9.35

Base Dissociation Constant (pKb)

-0.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

6466-1345 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with 6466-1345 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6466-1345?
Check Price and Availability of 6466-1345, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6466-1345 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6466-1345
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6466-1345
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6466-1345 available by request