6528-0324 Screening compound: 4'-hydroxy-3'-(4-methoxy-3-methylbenzoyl)-1-methyl-1'-[3-(morpholin-4-yl)propyl]-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione

6528-0324 Screening compound: 4'-hydroxy-3'-(4-methoxy-3-methylbenzoyl)-1-methyl-1'-[3-(morpholin-4-yl)propyl]-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione
6528-0324 Screening compound: 4'-hydroxy-3'-(4-methoxy-3-methylbenzoyl)-1-methyl-1'-[3-(morpholin-4-yl)propyl]-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 6528-0324
4'-hydroxy-3'-(4-methoxy-3-methylbenzoyl)-1-methyl-1'-[3-(morpholin-4-yl)propyl]-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6528-0324

Molecular Formula

C28H31N3O6 (C28 H31 N3 O6)

Compound Name

4'-hydroxy-3'-(4-methoxy-3-methylbenzoyl)-1-methyl-1'-[3-(morpholin-4-yl)propyl]-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione

IUPAC name

4'-hydroxy-3'-(4-methoxy-3-methylbenzoyl)-1-methyl-1'-[3-(morpholin-4-yl)propyl]-11'25'-tetrahydrospiro[indole-32'-pyrrole]-25'-dione

SMILES

Cc(cc(cc1)C(C(C(c(cccc2)c2N2C)(C2=O)N(CCCN2CCOCC2)C2=O)=C2O)=O)c1OC

InChI

InChI=1S/C28H31N3O6/c1-18-17-19(9-10-22(18)36-3)24(32)23-25(33)26(34)31(12-6-11-30-13-15-37-16-14-30)28(23)20-7-4-5-8-21(20)29(2)27(28)35/h4-5,7-10,17,33H,6,11-16H2,1-3H3/t28-/m0/s1

InChI Key

XQROHBSYWDSDHF-NDEPHWFRSA-N

MDL Number (MFCD)

MFCD04446859

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

505.57

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.232

Distribution Coefficient, logD

2.081

Water Solubility, LogSw

-2.80

Polar Surface Area

79.267

Acid Dissociation Constant (pKa)

9.74

Base Dissociation Constant (pKb)

7.01

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.30

6528-0324 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with 6528-0324 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6528-0324?
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What is the minimum amount of 6528-0324 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6528-0324
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6528-0324
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6528-0324 available by request