6635-0434 Screening compound: 2-{2-[(3-chlorophenyl)amino]-4-(4-fluorophenyl)-1,3-thiazol-5-yl}acetic acid

6635-0434 Screening compound: 2-{2-[(3-chlorophenyl)amino]-4-(4-fluorophenyl)-1,3-thiazol-5-yl}acetic acid
6635-0434 Screening compound: 2-{2-[(3-chlorophenyl)amino]-4-(4-fluorophenyl)-1,3-thiazol-5-yl}acetic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound 6635-0434
2-{2-[(3-chlorophenyl)amino]-4-(4-fluorophenyl)-1,3-thiazol-5-yl}acetic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6635-0434

Molecular Formula

C17H12ClFN2O2S (C17 H12 ClFN2 O2 S)

Compound Name

2-{2-[(3-chlorophenyl)amino]-4-(4-fluorophenyl)-1,3-thiazol-5-yl}acetic acid

IUPAC name

2-{2-[(3-chlorophenyl)amino]-4-(4-fluorophenyl)-13-thiazol-5-yl}acetic acid

SMILES

OC(Cc1c(-c(cc2)ccc2F)nc(Nc2cccc(Cl)c2)s1)=O

InChI

InChI=1S/C17H12ClFN2O2S/c18-11-2-1-3-13(8-11)20-17-21-16(14(24-17)9-15(22)23)10-4-6-12(19)7-5-10/h1-8H,9H2,(H,20,21)(H,22,23)

InChI Key

QCJUBGOWJPPAFP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03110172

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

362.81

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.248

Distribution Coefficient, logD

1.683

Water Solubility, LogSw

-5.44

Polar Surface Area

48.080

Acid Dissociation Constant (pKa)

3.84

Base Dissociation Constant (pKb)

2.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

6635-0434 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antiviral Library (67538 compounds)

Antibacterial Compounds Library (13827 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Immune system
  • animal
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 6635-0434 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6635-0434?
Check Price and Availability of 6635-0434, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6635-0434 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6635-0434
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6635-0434
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6635-0434 available by request