7147-0818 Screening compound: 2-[(1E)-2-(4-bromophenyl)ethenyl]-8-methoxyquinoline

7147-0818 Screening compound: 2-[(1E)-2-(4-bromophenyl)ethenyl]-8-methoxyquinoline
7147-0818 Screening compound: 2-[(1E)-2-(4-bromophenyl)ethenyl]-8-methoxyquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound 7147-0818
2-[(1E)-2-(4-bromophenyl)ethenyl]-8-methoxyquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

7147-0818

Molecular Formula

C18H14BrNO (C18 H14 BrNO)

Compound Name

2-[(1E)-2-(4-bromophenyl)ethenyl]-8-methoxyquinoline

IUPAC name

2-[(1E)-2-(4-bromophenyl)ethenyl]-8-methoxyquinoline

SMILES

COc1c2nc(/C=C/c(cc3)ccc3Br)ccc2ccc1

InChI

InChI=1S/C18H14BrNO/c1-21-17-4-2-3-14-8-12-16(20-18(14)17)11-7-13-5-9-15(19)10-6-13/h2-12H,1H3

InChI Key

LXWQVDJPHJEDSS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04216557

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

340.22

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

5.454

Distribution Coefficient, logD

5.453

Water Solubility, LogSw

-6.50

Polar Surface Area

17.194

Acid Dissociation Constant (pKa)

32.55

Base Dissociation Constant (pKb)

3.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

7147-0818 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Receptor-type Protein Tyrosine Phosphatases Library (3746 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Cancer
  • Digestive system
  • Nervous system
  • Female
  • Metabolic
  • Endocrine
Targets:
  • GPCR
  • Ion Channels
  • Phosphatases
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 7147-0818 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 7147-0818?
Check Price and Availability of 7147-0818, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 7147-0818 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 7147-0818
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 7147-0818
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 7147-0818 available by request