7152-3137 Screening compound: 1-(4-ethoxyphenyl)-7-fluoro-2-(5-propyl-1,3,4-thiadiazol-2-yl)-1H,2H,3H,9H-chromeno[2,3-c]pyrrole-3,9-dione

7152-3137 Screening compound: 1-(4-ethoxyphenyl)-7-fluoro-2-(5-propyl-1,3,4-thiadiazol-2-yl)-1H,2H,3H,9H-chromeno[2,3-c]pyrrole-3,9-dione
7152-3137 Screening compound: 1-(4-ethoxyphenyl)-7-fluoro-2-(5-propyl-1,3,4-thiadiazol-2-yl)-1H,2H,3H,9H-chromeno[2,3-c]pyrrole-3,9-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 7152-3137
1-(4-ethoxyphenyl)-7-fluoro-2-(5-propyl-1,3,4-thiadiazol-2-yl)-1H,2H,3H,9H-chromeno[2,3-c]pyrrole-3,9-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

7152-3137

Molecular Formula

C24H20FN3O4S (C24 H20 FN3 O4 S)

Compound Name

1-(4-ethoxyphenyl)-7-fluoro-2-(5-propyl-1,3,4-thiadiazol-2-yl)-1H,2H,3H,9H-chromeno[2,3-c]pyrrole-3,9-dione

IUPAC name

1-(4-ethoxyphenyl)-7-fluoro-2-(5-propyl-134-thiadiazol-2-yl)-1H2H3H9H-chromeno[23-c]pyrrole-39-dione

SMILES

CCCc1nnc(N(C(C2=C3Oc(ccc(F)c4)c4C2=O)c(cc2)ccc2OCC)C3=O)s1

InChI

InChI=1S/C24H20FN3O4S/c1-3-5-18-26-27-24(33-18)28-20(13-6-9-15(10-7-13)31-4-2)19-21(29)16-12-14(25)8-11-17(16)32-22(19)23(28)30/h6-12,20H,3-5H2,1-2H3/t20-/m1/s1

InChI Key

YYQDPDFMPOKGNK-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD06645316

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.953

Distribution Coefficient, logD

4.953

Water Solubility, LogSw

-4.69

Polar Surface Area

67.059

Acid Dissociation Constant (pKa)

11.10

Base Dissociation Constant (pKb)

-8.39

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

7152-3137 in Drug Discovery

Included in Screening Libraries

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 7152-3137 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 7152-3137?
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What is the minimum amount of 7152-3137 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 7152-3137
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 7152-3137
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 7152-3137 available by request