7287-0374 Screening compound: 2-(1H-1,3-benzodiazol-2-yl)-3-phenyl-2H-1,4-benzothiazine

7287-0374 Screening compound: 2-(1H-1,3-benzodiazol-2-yl)-3-phenyl-2H-1,4-benzothiazine
7287-0374 Screening compound: 2-(1H-1,3-benzodiazol-2-yl)-3-phenyl-2H-1,4-benzothiazine alternative view

Chemical Structure Depiction of ChemDiv screening compound 7287-0374
2-(1H-1,3-benzodiazol-2-yl)-3-phenyl-2H-1,4-benzothiazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

7287-0374

Molecular Formula

C21H15N3S (C21 H15 N3 S)

Compound Name

2-(1H-1,3-benzodiazol-2-yl)-3-phenyl-2H-1,4-benzothiazine

IUPAC name

2-(1H-13-benzodiazol-2-yl)-3-phenyl-2H-14-benzothiazine

SMILES

c(cc1)ccc1C1=Nc(cccc2)c2SC1c1nc(cccc2)c2[nH]1

InChI

InChI=1S/C21H15N3S/c1-2-8-14(9-3-1)19-20(25-18-13-7-6-12-17(18)22-19)21-23-15-10-4-5-11-16(15)24-21/h1-13,20H,(H,23,24)/t20-/m1/s1

InChI Key

JIHQIRFYNAQVNT-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD03955602

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

341.44

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.886

Distribution Coefficient, logD

2.797

Water Solubility, LogSw

-4.94

Polar Surface Area

27.016

Acid Dissociation Constant (pKa)

12.34

Base Dissociation Constant (pKb)

9.49

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

4.80

7287-0374 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 7287-0374 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 7287-0374?
Check Price and Availability of 7287-0374, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 7287-0374 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 7287-0374
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 7287-0374
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 7287-0374 available by request