7376-0072 Screening compound: N-{5-[(4-chlorophenyl)methyl]-1,4,5,6-tetrahydro-1,3,5-triazin-2-yl}-6-ethyl-4-methylquinazolin-2-amine

7376-0072 Screening compound: N-{5-[(4-chlorophenyl)methyl]-1,4,5,6-tetrahydro-1,3,5-triazin-2-yl}-6-ethyl-4-methylquinazolin-2-amine
7376-0072 Screening compound: N-{5-[(4-chlorophenyl)methyl]-1,4,5,6-tetrahydro-1,3,5-triazin-2-yl}-6-ethyl-4-methylquinazolin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 7376-0072
N-{5-[(4-chlorophenyl)methyl]-1,4,5,6-tetrahydro-1,3,5-triazin-2-yl}-6-ethyl-4-methylquinazolin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

7376-0072

Molecular Formula

C21H23ClN6 (C21 H23 ClN6)

Compound Name

N-{5-[(4-chlorophenyl)methyl]-1,4,5,6-tetrahydro-1,3,5-triazin-2-yl}-6-ethyl-4-methylquinazolin-2-amine

IUPAC name

N-{5-[(4-chlorophenyl)methyl]-1456-tetrahydro-135-triazin-2-yl}-6-ethyl-4-methylquinazolin-2-amine

SMILES

CCc1ccc2nc(NC3=NCN(Cc(cc4)ccc4Cl)CN3)nc(C)c2c1

InChI

InChI=1S/C21H23ClN6/c1-3-15-6-9-19-18(10-15)14(2)25-21(26-19)27-20-23-12-28(13-24-20)11-16-4-7-17(22)8-5-16/h4-10H,3,11-13H2,1-2H3,(H2,23,24,25,26,27)

InChI Key

ZQLVPWPYMJWMDT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05685390

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.91

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.138

Distribution Coefficient, logD

-0.158

Water Solubility, LogSw

-5.59

Polar Surface Area

53.042

Acid Dissociation Constant (pKa)

13.84

Base Dissociation Constant (pKb)

10.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

7376-0072 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 7376-0072 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 7376-0072?
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What is the minimum amount of 7376-0072 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 7376-0072
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 7376-0072
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 7376-0072 available by request