7610-3451 Screening compound: N-(4-chloro-2,5-dimethoxyphenyl)-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

7610-3451 Screening compound: N-(4-chloro-2,5-dimethoxyphenyl)-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
7610-3451 Screening compound: N-(4-chloro-2,5-dimethoxyphenyl)-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 7610-3451
N-(4-chloro-2,5-dimethoxyphenyl)-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

7610-3451

Molecular Formula

C23H19ClF2N4O4 (C23 H19 ClF2 N4 O4)

Compound Name

N-(4-chloro-2,5-dimethoxyphenyl)-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

IUPAC name

N-(4-chloro-25-dimethoxyphenyl)-7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[15-a]pyrimidine-3-carboxamide

SMILES

COc(cc1)ccc1-c(cc(C(F)F)n1nc2)nc1c2C(Nc(c(OC)c1)cc(OC)c1Cl)=O

InChI

InChI=1S/C23H19ClF2N4O4/c1-32-13-6-4-12(5-7-13)16-9-18(21(25)26)30-22(28-16)14(11-27-30)23(31)29-17-10-19(33-2)15(24)8-20(17)34-3/h4-11,21H,1-3H3,(H,29,31)

InChI Key

JAFZUDDZKLTXEV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02373354

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.88

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.727

Distribution Coefficient, logD

4.383

Water Solubility, LogSw

-4.97

Polar Surface Area

64.366

Acid Dissociation Constant (pKa)

7.32

Base Dissociation Constant (pKb)

-1.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

7610-3451 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with 7610-3451 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 7610-3451?
Check Price and Availability of 7610-3451, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 7610-3451 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 7610-3451
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 7610-3451
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 7610-3451 available by request