8001-2823 Screening compound: 2-chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]-4,5-difluorobenzamide

8001-2823 Screening compound: 2-chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]-4,5-difluorobenzamide
8001-2823 Screening compound: 2-chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]-4,5-difluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8001-2823
2-chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]-4,5-difluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8001-2823

Molecular Formula

C16H7ClF4N2OS (C16 H7 ClF4 N2 OS)

Compound Name

2-chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]-4,5-difluorobenzamide

IUPAC name

2-chloro-N-[4-(34-difluorophenyl)-13-thiazol-2-yl]-45-difluorobenzamide

SMILES

O=C(c(cc(c(F)c1)F)c1Cl)Nc1nc(-c(cc2)cc(F)c2F)cs1

InChI

InChI=1S/C16H7ClF4N2OS/c17-9-5-13(21)12(20)4-8(9)15(24)23-16-22-14(6-25-16)7-1-2-10(18)11(19)3-7/h1-6H,(H,22,23,24)

InChI Key

TXEMYTBXGONECF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00472889

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.76

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.759

Distribution Coefficient, logD

5.489

Water Solubility, LogSw

-6.15

Polar Surface Area

33.104

Acid Dissociation Constant (pKa)

7.46

Base Dissociation Constant (pKb)

-1.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8001-2823 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with 8001-2823 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8001-2823?
Check Price and Availability of 8001-2823, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8001-2823 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8001-2823
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8001-2823
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8001-2823 available by request