8002-0385 Screening compound: 2-(4-chlorobenzoyl)-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine

8002-0385 Screening compound: 2-(4-chlorobenzoyl)-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine
8002-0385 Screening compound: 2-(4-chlorobenzoyl)-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8002-0385
2-(4-chlorobenzoyl)-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8002-0385

Molecular Formula

C18H15ClN2OS (C18 H15 ClN2 OS)

Compound Name

2-(4-chlorobenzoyl)-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine

IUPAC name

2-(4-chlorobenzoyl)-5H6H7H8H-thieno[23-b]quinolin-3-amine

SMILES

Nc1c(C(c(cc2)ccc2Cl)=O)sc2c1cc(CCCC1)c1n2

InChI

InChI=1S/C18H15ClN2OS/c19-12-7-5-10(6-8-12)16(22)17-15(20)13-9-11-3-1-2-4-14(11)21-18(13)23-17/h5-9H,1-4,20H2

InChI Key

LDTPLXPHPYRTJH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00475825

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

342.85

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.093

Distribution Coefficient, logD

5.075

Water Solubility, LogSw

-5.55

Polar Surface Area

44.234

Acid Dissociation Constant (pKa)

19.66

Base Dissociation Constant (pKb)

6.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

8002-0385 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • Epigenetic
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 8002-0385 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8002-0385?
Check Price and Availability of 8002-0385, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8002-0385 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8002-0385
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8002-0385
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8002-0385 available by request