8003-1378 Screening compound: N'-[(E)-(4-chloro-3-nitrophenyl)methylidene]-2,2-diphenylcyclopropane-1-carbohydrazide

8003-1378 Screening compound: N'-[(E)-(4-chloro-3-nitrophenyl)methylidene]-2,2-diphenylcyclopropane-1-carbohydrazide
8003-1378 Screening compound: N'-[(E)-(4-chloro-3-nitrophenyl)methylidene]-2,2-diphenylcyclopropane-1-carbohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8003-1378
N'-[(E)-(4-chloro-3-nitrophenyl)methylidene]-2,2-diphenylcyclopropane-1-carbohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8003-1378

Molecular Formula

C23H18ClN3O3 (C23 H18 ClN3 O3)

Compound Name

N'-[(E)-(4-chloro-3-nitrophenyl)methylidene]-2,2-diphenylcyclopropane-1-carbohydrazide

IUPAC name

N'-[(E)-(4-chloro-3-nitrophenyl)methylidene]-22-diphenylcyclopropane-1-carbohydrazide

SMILES

[O-][N+](c(cc(/C=N/NC(C(C1)C1(c1ccccc1)c1ccccc1)=O)cc1)c1Cl)=O

InChI

InChI=1S/C23H18ClN3O3/c24-20-12-11-16(13-21(20)27(29)30)15-25-26-22(28)19-14-23(19,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-13,15,19H,14H2,(H,26,28)/t19-/m1/s1

InChI Key

RLGULENBDNPZNJ-LJQANCHMSA-N

MDL Number (MFCD)

MFCD00588951

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.87

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.357

Distribution Coefficient, logD

5.024

Water Solubility, LogSw

-6.07

Polar Surface Area

68.615

Acid Dissociation Constant (pKa)

7.34

Base Dissociation Constant (pKb)

1.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.00

8003-1378 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with 8003-1378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8003-1378?
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What is the minimum amount of 8003-1378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8003-1378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8003-1378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8003-1378 available by request