8003-6129 Screening compound: 7-tert-butyl-2-(4-fluorobenzoyl)-4-(thiophen-2-yl)-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine

8003-6129 Screening compound: 7-tert-butyl-2-(4-fluorobenzoyl)-4-(thiophen-2-yl)-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine
8003-6129 Screening compound: 7-tert-butyl-2-(4-fluorobenzoyl)-4-(thiophen-2-yl)-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8003-6129
7-tert-butyl-2-(4-fluorobenzoyl)-4-(thiophen-2-yl)-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8003-6129

Molecular Formula

C26H25FN2OS2 (C26 H25 FN2 OS2)

Compound Name

7-tert-butyl-2-(4-fluorobenzoyl)-4-(thiophen-2-yl)-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine

IUPAC name

7-tert-butyl-2-(4-fluorobenzoyl)-4-(thiophen-2-yl)-5H6H7H8H-thieno[23-b]quinolin-3-amine

SMILES

CC(C)(C)C(CC1)Cc2c1c(-c1cccs1)c(c(N)c(C(c(cc1)ccc1F)=O)s1)c1n2

InChI

InChI=1S/C26H25FN2OS2/c1-26(2,3)15-8-11-17-18(13-15)29-25-21(20(17)19-5-4-12-31-19)22(28)24(32-25)23(30)14-6-9-16(27)10-7-14/h4-7,9-10,12,15H,8,11,13,28H2,1-3H3/t15-/m1/s1

InChI Key

QOTKOAORRKPRKS-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD00744627

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.63

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

7.548

Distribution Coefficient, logD

7.515

Water Solubility, LogSw

-5.98

Polar Surface Area

44.980

Acid Dissociation Constant (pKa)

20.49

Base Dissociation Constant (pKb)

6.30

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.80

8003-6129 in Drug Discovery

Included in Screening Libraries

Regenerative Medicine Focused Library (23016 compounds)

New Agro Library (44492 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Agro:
  • Agro
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 8003-6129 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8003-6129?
Check Price and Availability of 8003-6129, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8003-6129 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8003-6129
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8003-6129
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8003-6129 available by request