8004-2365 Screening compound: 2-chloro-5-(piperidine-1-sulfonyl)-N-(1,3-thiazol-2-yl)benzamide

8004-2365 Screening compound: 2-chloro-5-(piperidine-1-sulfonyl)-N-(1,3-thiazol-2-yl)benzamide
8004-2365 Screening compound: 2-chloro-5-(piperidine-1-sulfonyl)-N-(1,3-thiazol-2-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8004-2365
2-chloro-5-(piperidine-1-sulfonyl)-N-(1,3-thiazol-2-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8004-2365

Molecular Formula

C15H16ClN3O3S2 (C15 H16 ClN3 O3 S2)

Compound Name

2-chloro-5-(piperidine-1-sulfonyl)-N-(1,3-thiazol-2-yl)benzamide

IUPAC name

2-chloro-5-(piperidine-1-sulfonyl)-N-(13-thiazol-2-yl)benzamide

SMILES

O=C(c(cc(cc1)S(N2CCCCC2)(=O)=O)c1Cl)Nc1nccs1

InChI

InChI=1S/C15H16ClN3O3S2/c16-13-5-4-11(24(21,22)19-7-2-1-3-8-19)10-12(13)14(20)18-15-17-6-9-23-15/h4-6,9-10H,1-3,7-8H2,(H,17,18,20)

InChI Key

XZHHCYQZMFZCNZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00745376

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.9

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.161

Distribution Coefficient, logD

2.709

Water Solubility, LogSw

-3.82

Polar Surface Area

65.519

Acid Dissociation Constant (pKa)

7.14

Base Dissociation Constant (pKb)

0.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

8004-2365 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS targets activity set (6557 compounds)

Dark Chemical Matter Library (18430 compounds)

Human GPCR Annotated Library (5539 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Structure:
  • Pool

References: we are preparing a list of scientific research reports with 8004-2365 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8004-2365?
Check Price and Availability of 8004-2365, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8004-2365 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8004-2365
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8004-2365
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8004-2365 available by request