8005-3411 Screening compound: 4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-amine

8005-3411 Screening compound: 4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-amine
8005-3411 Screening compound: 4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8005-3411
4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8005-3411

Molecular Formula

C15H12N2S (C15 H12 N2 S)

Compound Name

4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-amine

IUPAC name

4-{[11'-biphenyl]-4-yl}-13-thiazol-2-amine

SMILES

Nc1nc(-c(cc2)ccc2-c2ccccc2)cs1

InChI

InChI=1S/C15H12N2S/c16-15-17-14(10-18-15)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-10H,(H2,16,17)

InChI Key

HTAUVJPDFDVVHV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00047059

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

252.34

Hydrogen Bond Acceptors Count

1.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

4.333

Distribution Coefficient, logD

4.333

Water Solubility, LogSw

-4.81

Polar Surface Area

30.499

Acid Dissociation Constant (pKa)

21.44

Base Dissociation Constant (pKb)

2.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8005-3411 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Human Receptors Annotated Library (5376 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Receptor-type Protein Tyrosine Phosphatases Library (3746 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
  • Cancer
  • Digestive system
  • Nervous system
  • Female
  • Metabolic
  • Endocrine
Targets:
  • GPCR
  • Ion Channels
  • Phosphatases
  • Phosphatases
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8005-3411 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8005-3411?
Check Price and Availability of 8005-3411, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8005-3411 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8005-3411
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8005-3411
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8005-3411 available by request